I had 2 occasions where my virtual machine couldn’t start. The error message as similar to:
Could not find a registered CD/DVD image with UUID {90780d30-7262-4296-9d45-b1fdf718e414}.
Result Code: 0x80070057 Component: VirtualBox Interface: IVirtualBox {e1d95593-f579-4f47-b489-0b67181014e1}
To fix the problem, edit the machine XML file in .VirtualBox\Machines\{vm_name}\{vm_name}.xml and replaced the line with the UUID specified with the line:
<DVDDrive passthrough="false"/>
That disconnected the CD/DVD and I was able to start the virtual machine again.
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